Research, Life Sciences Hot Metal Team Research, Life Sciences Hot Metal Team

Hot Metal Campus Celebrates D’Amore Lab’s NIH Grant

Congratulations to the D’Amore Lab, led by Dr. Antonio D’Amore, which in July 2026 was awarded an NIH National Heart, Lung, and Blood Institute grant totaling nearly $800,000 for the project: Structural Biomimicry to Improve Engineered Heart Valve Leaflet Function and Remodeling. The D’Amore Lab, which is located at Bridgeside Point II on the Hot Metal Campus, will advance bioengineering approaches to treat pediatric heart valve diseases by exploring the use of tissue engineered heart valves (TEHVs), which mimic the structure and function of natural heart valve tissue, to restore heart valve function.

Read More
Research, AI, Corporate Innovation Hot Metal Team Research, AI, Corporate Innovation Hot Metal Team

Avista Therapeutics Expands Its AI Gene Therapy Platform

Avista Therapeutics has expanded its gene therapy platform to take on some of the field's hardest delivery problems. The company recently announced that it is scaling up its capsid design program with artificial intelligence and adding a new Innovation Platform, work it says targets long-standing barriers in AAV capsid engineering, large gene delivery and manufacturing.

Read More
Research Pearl Kaplan Research Pearl Kaplan

Fully Immersive Virtual Reality for Chronic Pain: New Scoping Article Highlights Promise and Ideas for Future Work

Virtual reality brings to mind immersive environments, interactive games, and training simulation experiences. But rehabilitation researchers are also exploring how virtual reality can help people with chronic pain. To shed light on this new field, which was described as being in a “discovery phase,” a team of researchers from Tufts University, the University of Pittsburgh, and the U.S. Department of Veterans Affairs published a scoping review in Virtual Worlds in January 2026.

Read More
Research, Community & People Neema Tavakolian Research, Community & People Neema Tavakolian

EvolvingSTEM Brings Lab Experiments Straight Into the Classroom

Based out of Bridgeside Point II in Hot Metal Campus, EvolvingSTEM is a science outreach program that brings evolution and microbiology research directly into classrooms across the Pittsburgh region. Run through Professor Vaughn Cooper’s lab in the Department of Microbiology & Molecular Genetics at the University of Pittsburgh, the program equips students from grades 6 through 12 with the tools and framework to conduct real experiments on bacterial evolution.

Read More
Research, Community & People Pearl Kaplan Research, Community & People Pearl Kaplan

How ENGAGE’s Community Learning Shapes Stroke Recovery

‍ ‍

ENGAGE focuses on the social side of stroke recovery, helping people rebuild confidence and reconnect with their communities. This group intervention, which was co-designed by community members who are stroke survivors, was tested by a multi-university team of researchers led by Dr. Elizabeth Skidmore at the University of Pittsburgh’s Department of Occupational Therapy.

Read More
Research, Life Sciences Isabella Fonseca Research, Life Sciences Isabella Fonseca

The Implant System that Seeks to Restore Vision Loss

Current treatments for geographic atrophy in age-related macular degeneration (AMD) can slow the progression of vision loss but they do not restore vision. To address this issue, a team of researchers is developing the photovoltaic retina implant microarray (PRIMA) system, an implant system that uses infrared light to restore lost sight.

Read More
Research Pearl Kaplan Research Pearl Kaplan

If You Have a Question, Others Probably Do Too

Do I belong here? What do I wish I knew when I started this job, degree, or program? A team of University of Pittsburgh researchers used the power of reflecting on these ever-present questions to develop a three-session, evidence-based ecological belonging program, Supporting Hardiness and Inclusion for New Endeavors (SHINE), for entry-level occupational therapy doctorate students.

Read More
Research Pearl Kaplan Research Pearl Kaplan

Physical Therapy Needs to be Closer to Home

Your location shouldn’t affect your ability to participate in a physical therapy program. To address the burden of long travel distances to physical therapy for older adults with knee osteoarthritis living in rural areas, University of Pittsburgh researchers conducted a pilot feasibility study of a novel hybrid in-person and telerehabilitation program that was found to be safe and feasible.

Read More
Research, Life Sciences Isabella Fonseca Research, Life Sciences Isabella Fonseca

How Genetic and Environmental Factors Impact Risk of Orofacial Clefts in the Philippines

Hot Metal Campus researchers, including Mary L. Marazita, PhD, and Seth Weinberg, PhD, from UPitt’s Center for Craniofacial and Dental Genetics, as well as the Schools of Medicine and Public Health, are investigating the interaction between maternal smoking and vitamin use, and how these factors influence genes to cause orofacial clefts in Filipinos.

Read More
Research Pearl Kaplan Research Pearl Kaplan

We Can Change Our Homes as We Age: Becoming More CAPABLE

As we get older and our needs and goals change, so must our home environment ensure ongoing comfort, safety, and dignity in the places where our most precious memories are held. To help older adults continue to live in their home and safely meet their goals, University of Pittsburgh researchers in the Department of Occupational Therapy recently presented highlights from an ongoing CAPABLE study.

Read More